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Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis

Virulence-linked pathways in opportunistic pathogens are putative therapeutic targets that may be associated with less potential for resistance than targets in growth-essential pathways. However, efficacy of virulence-linked targets may be affected by the contribution of virulence-related genes to m...

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Detalles Bibliográficos
Autores principales: Bartell, Jennifer A., Blazier, Anna S., Yen, Phillip, Thøgersen, Juliane C., Jelsbak, Lars, Goldberg, Joanna B., Papin, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344303/
https://www.ncbi.nlm.nih.gov/pubmed/28266498
http://dx.doi.org/10.1038/ncomms14631