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Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis
Virulence-linked pathways in opportunistic pathogens are putative therapeutic targets that may be associated with less potential for resistance than targets in growth-essential pathways. However, efficacy of virulence-linked targets may be affected by the contribution of virulence-related genes to m...
Autores principales: | Bartell, Jennifer A., Blazier, Anna S., Yen, Phillip, Thøgersen, Juliane C., Jelsbak, Lars, Goldberg, Joanna B., Papin, Jason A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344303/ https://www.ncbi.nlm.nih.gov/pubmed/28266498 http://dx.doi.org/10.1038/ncomms14631 |
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