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Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non–Small Cell Lung Cancer
Loss of basement membrane (BM) integrity is typically associated with cancer. Nidogen-1 is an essential component of the BM. Nidogen-1 is a substrate for cathepsin-S (CatS) which is released into the tumor microenvironment. Measuring nidogen-1 degraded by CatS may therefore have biomarker potential...
Autores principales: | Willumsen, Nicholas, Bager, Cecilie L., Leeming, Diana J., Bay-Jensen, Anne-Christine, Karsdal, Morten A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344320/ https://www.ncbi.nlm.nih.gov/pubmed/28282545 http://dx.doi.org/10.1016/j.neo.2017.01.008 |
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