Systemic thioridazine in combination with dicloxacillin against early aortic graft infections caused by Staphylococcus aureus in a porcine model: In vivo results do not reproduce the in vitro synergistic activity

INTRODUCTION: Conservative treatment solutions against aortic prosthetic vascular graft infection (APVGI) for inoperable patients are limited. The combination of antibiotics with antibacterial helper compounds, such as the neuroleptic drug thioridazine (TDZ), should be explored. AIM: To investigate...

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Detalles Bibliográficos
Autores principales: Stenger, Michael, Behr-Rasmussen, Carsten, Klein, Kasper, Grønnemose, Rasmus B., Andersen, Thomas Emil, Klitgaard, Janne K., Kolmos, Hans Jørn, Lindholt, Jes S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344393/
https://www.ncbi.nlm.nih.gov/pubmed/28278183
http://dx.doi.org/10.1371/journal.pone.0173362

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