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Complement effectors, C5a and C3a, in cystic fibrosis lung fluid correlate with disease severity

In cystic fibrosis (CF), lung damage is mediated by a cycle of obstruction, infection, inflammation and tissue destruction. The complement system is a major mediator of inflammation for many diseases with the effectors C5a and C3a often playing important roles. We have previously shown in a small pi...

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Detalles Bibliográficos
Autores principales: Hair, Pamela S., Sass, Laura A., Vazifedan, Turaj, Shah, Tushar A., Krishna, Neel K., Cunnion, Kenji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344399/
https://www.ncbi.nlm.nih.gov/pubmed/28278205
http://dx.doi.org/10.1371/journal.pone.0173257