Cargando…
The role of platelet and endothelial GARP in thrombosis and hemostasis
BACKGROUND: Glycoprotein-A Repetitions Predominant protein (GARP or LRRC32) is present on among others human platelets and endothelial cells. Evidence for its involvement in thrombus formation was suggested by full knockout of GARP in zebrafish. OBJECTIVES: To evaluate the role of GARP in platelet p...
Autores principales: | Vermeersch, Elien, Denorme, Frederik, Maes, Wim, De Meyer, Simon F., Vanhoorelbeke, Karen, Edwards, Justin, Shevach, Ethan M., Unutmaz, Derya, Fujii, Hodaka, Deckmyn, Hans, Tersteeg, Claudia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344406/ https://www.ncbi.nlm.nih.gov/pubmed/28278197 http://dx.doi.org/10.1371/journal.pone.0173329 |
Ejemplares similares
-
Functional Genomics for the Identification of Modulators of Platelet-Dependent Thrombus Formation
por: Vermeersch, Elien, et al.
Publicado: (2018) -
von Willebrand Factor and Platelet Glycoprotein Ib: A Thromboinflammatory Axis in Stroke
por: Denorme, Frederik, et al.
Publicado: (2019) -
Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer
por: de Streel, Grégoire, et al.
Publicado: (2020) -
Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura
por: Deforche, Louis, et al.
Publicado: (2016) -
Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease
por: Denorme, Frederik, et al.
Publicado: (2017)