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MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866

Our previous study indicated that overexpression of nicotinamide phosphoribosyltransferase (NAMPT) aggravated acute lung injury, while knockdown of NAMPT expression attenuated ventilator-induced lung injury. Recently, we found that meta-carborane-butyl-3-(3-pyridinyl)-2E-propenamide (MC-PPEA, MC4),...

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Detalles Bibliográficos
Autores principales:	Huang, Peixin, Lee, Mark W, Sadrerafi, Keivan, Heruth, Daniel P, Zhang, Li Q, Maulik, Dev, Ye, Shui Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344436/ https://www.ncbi.nlm.nih.gov/pubmed/28424540 http://dx.doi.org/10.2147/DDDT.S125349

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