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Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis

Activity of H3K9 histone methyltransferase G9a is reportedly induced by transforming growth factor-β1 (TGF-β1) and plays an important role in the progression of cancer and fibrosis. In this study, we investigated whether inhibition of G9a-mediated H3K9 methylation attenuates peritoneal fibrosis in m...

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Detalles Bibliográficos
Autores principales:	Maeda, Kazuya, Doi, Shigehiro, Nakashima, Ayumu, Nagai, Takuo, Irifuku, Taisuke, Ueno, Toshinori, Masaki, Takao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344517/ https://www.ncbi.nlm.nih.gov/pubmed/28278257 http://dx.doi.org/10.1371/journal.pone.0173706

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