Cargando…
Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species
BACKGROUND: Interleukin-32 (IL-32) is expressed in lesions of patients with American Tegumentary Leishmaniasis (ATL), but its precise role in the disease remains unknown. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, silencing and overexpression of IL-32 was performed in THP-1-derived macrop...
Autores principales: | dos Santos, Jéssica Cristina, Heinhuis, Bas, Gomes, Rodrigo Saar, Damen, Michelle S. M. A., Real, Fernando, Mortara, Renato A., Keating, Samuel T., Dinarello, Charles A., Joosten, Leo A. B., Ribeiro-Dias, Fátima |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344527/ https://www.ncbi.nlm.nih.gov/pubmed/28241012 http://dx.doi.org/10.1371/journal.pntd.0005413 |
Ejemplares similares
-
The NOD2 receptor is crucial for immune responses towards New World Leishmania species
por: dos Santos, Jéssica Cristina, et al.
Publicado: (2017) -
IL-32γ promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis
por: Gomes, Rodrigo Saar, et al.
Publicado: (2017) -
Fusion between Leishmania amazonensis and Leishmania major Parasitophorous Vacuoles: Live Imaging of Coinfected Macrophages
por: Real, Fernando, et al.
Publicado: (2010) -
The Diverse and Dynamic Nature of Leishmania Parasitophorous Vacuoles Studied by Multidimensional Imaging
por: Real, Fernando, et al.
Publicado: (2012) -
Lipophosphoglycan From Dermotropic New World Leishmania Upregulates Interleukin-32 and Proinflammatory Cytokines Through TLR4 and NOD2 Receptors
por: Silveira, Murilo Barros, et al.
Publicado: (2022)