On How Fas Apoptosis-Independent Pathways Drive T Cell Hyperproliferation and Lymphadenopathy in lpr Mice

Fas induces massive apoptosis in T cells after repeated in vitro T cell receptor (TCR) stimulation and is critical for lymphocyte homeostasis in Fas-deficient (lpr) mice. Although the in vitro Fas apoptotic mechanism has been defined, there is a large conceptual gap between this in vitro phenomenon...

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Detalles Bibliográficos
Autores principales: Balomenos, Dimitrios, Shokri, Rahman, Daszkiewicz, Lidia, Vázquez-Mateo, Cristina, Martínez-A, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344898/
https://www.ncbi.nlm.nih.gov/pubmed/28344578
http://dx.doi.org/10.3389/fimmu.2017.00237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344898/
https://www.ncbi.nlm.nih.gov/pubmed/28344578
http://dx.doi.org/10.3389/fimmu.2017.00237

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