Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Development of systems that reconstitute hallmark features of human pancreatic intraepithelial neoplasia (PanINs), the precursor to pancreatic ductal adenocarcinoma, could generate new strategies for early diagnosis and intervention. However, human cell-based PanIN models with defined mutations are...

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Detalles Bibliográficos
Autores principales: Lee, Jonghyeob, Snyder, Emily R., Liu, Yinghua, Gu, Xueying, Wang, Jing, Flowers, Brittany M., Kim, Yoo Jung, Park, Sangbin, Szot, Gregory L., Hruban, Ralph H., Longacre, Teri A., Kim, Seung K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344977/
https://www.ncbi.nlm.nih.gov/pubmed/28272465
http://dx.doi.org/10.1038/ncomms14686

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