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Proteomic Analysis of Host Cell Protein Dynamics in the Culture Supernatants of Antibody-Producing CHO Cells

Chinese hamster ovary (CHO) cells are the most common cell line used for the production of therapeutic proteins including monoclonal antibodies (mAbs). Host cell proteins (HCPs), secreted and released from lysed cells, accumulate extracellularly during the cultures of recombinant CHO (rCHO) cells, p...

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Detalles Bibliográficos
Autores principales:	Park, Jin Hyoung, Jin, Jong Hwa, Lim, Myung Sin, An, Hyun Joo, Kim, Jong Won, Lee, Gyun Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345005/ https://www.ncbi.nlm.nih.gov/pubmed/28281648 http://dx.doi.org/10.1038/srep44246

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