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Auto-phosphorylation Represses Protein Kinase R Activity
The central role of protein kinases in controlling disease processes has spurred efforts to develop pharmaceutical regulators of their activity. A rational strategy to achieve this end is to determine intrinsic auto-regulatory processes, then selectively target these different states of kinases to r...
Autores principales: | Wang, Die, de Weerd, Nicole A., Willard, Belinda, Polekhina, Galina, Williams, Bryan R. G., Sadler, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345052/ https://www.ncbi.nlm.nih.gov/pubmed/28281686 http://dx.doi.org/10.1038/srep44340 |
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