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MiR-34a-5p promotes multi-chemoresistance of osteosarcoma through down-regulation of the DLL1 gene

MiR-34a-5p has been implicated in the tumorigenesis and progression of several types of cancer. However, the role of miR-34a-5p in osteosarcoma (OS) remains largely unknown. This study was performed in two multi-chemosensitive (G-292 and MG63.2) and two resistant (SJSA-1 and MNNG/HOS) OS cell lines....

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Detalles Bibliográficos
Autores principales: Pu, Youguang, Zhao, Fangfang, Wang, Haiyan, Cai, Shanbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345075/
https://www.ncbi.nlm.nih.gov/pubmed/28281638
http://dx.doi.org/10.1038/srep44218