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Notch signaling plays a crucial role in cancer stem-like cells maintaining stemness and mediating chemotaxis in renal cell carcinoma

BACKGROUND: Cancer stem cells (CSCs) are correlated with the initiation, chemoresistance and relapse of tumors. Notch pathway has been reported to function in CSCs maintenance, but whether it is involved in renal cell carcinoma (RCC) CSCs maintaining stemness remain unclear. This study aims to explo...

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Detalles Bibliográficos
Autores principales:	Xiao, Wei, Gao, Zhiyong, Duan, Yixing, Yuan, Wuxiong, Ke, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345133/ https://www.ncbi.nlm.nih.gov/pubmed/28279221 http://dx.doi.org/10.1186/s13046-017-0507-3

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