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Sox9 transcriptionally regulates Wnt signaling in intestinal epithelial stem cells in hypomethylated crypts in the diabetic state

BACKGROUND: Distinctive structures called crypts harbor intestinal epithelial stem cells (IESCs) which generate progenitor and terminally differentiated cells in the intestinal epithelium. Mammalian IESCs and their daughter cells require the participation of DNA methylation and the transcription fac...

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Detalles Bibliográficos
Autores principales: Huang, Can-Ze, Xu, Ji-Hao, Zhong, Wa, Xia, Zhong-Sheng, Wang, Si-Yi, Cheng, Di, Li, Jie-Yao, Wu, Ting-Feng, Chen, Qi-Kui, Yu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345140/
https://www.ncbi.nlm.nih.gov/pubmed/28279198
http://dx.doi.org/10.1186/s13287-017-0507-4