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CD117(+)CD44(+) Stem T Cells Develop in the Thymus and Potently Suppress T-cell Proliferation by Modulating the CTLA-4 Pathway

BACKGROUND: CD117 is expressed on double-negative (DN; CD4(–)CD8(–)) cells (Nat Rev Immunol 14:529–545; 2014), but whether it is expressed in other stages and its subsequent functions are unclear. We used an improved method of flow cytometry to analyze different populations of thymocytes (Sci Rep 4:...

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Detalles Bibliográficos
Autores principales:	Wei, Yang, Hu, Zhansheng, Gu, Wen, Liu, Gang, Shi, Bingyin, Liu, Enqi, Liu, Tie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345162/ https://www.ncbi.nlm.nih.gov/pubmed/28279199 http://dx.doi.org/10.1186/s13287-017-0495-4

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