Cargando…

Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes

BACKGROUND: Cardiotoxicity remains an important concern in drug discovery. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have become an attractive platform to evaluate cardiotoxicity. However, the consistency between human embryonic stem cell-derived cardiomyocytes (hESC-CMs) and hum...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Qi, Wang, Xijie, Wang, Shuyan, Song, Zheng, Wang, Jiaxian, Ma, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345165/ https://www.ncbi.nlm.nih.gov/pubmed/28279214 http://dx.doi.org/10.1186/s13287-017-0473-x

Ejemplares similares

Modelling cadmium‐induced cardiotoxicity using human pluripotent stem cell‐derived cardiomyocytes
por: Shen, Jiaxi, et al.
Publicado: (2018)

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes
por: Maillet, Agnes, et al.
Publicado: (2016)

Cardiotoxicity of Antineoplastic Therapies and Applications of Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Huang, Mo-Fan, et al.
Publicado: (2021)

Development and evaluation of next-generation cardiotoxicity assay based on embryonic stem cell-derived cardiomyocytes
por: Ryu, Bokyeong, et al.
Publicado: (2020)

Human Pluripotent Stem Cell-Derived Cardiomyocytes for Assessment of Anticancer Drug-Induced Cardiotoxicity
por: Schwach, Verena, et al.
Publicado: (2020)

Evaluation of the Cardiotoxicity of Mitragynine and Its Analogues Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Lu, Jun, et al.
Publicado: (2014)

Liensinine- and Neferine-Induced Cardiotoxicity in Primary Neonatal Rat Cardiomyocytes and Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Yu, Yangyang, et al.
Publicado: (2016)

An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes
por: Wang, Ruiying, et al.
Publicado: (2019)

Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes
por: Cao, Lu, et al.
Publicado: (2020)

Cardiotoxicity induced by the combination therapy of chloroquine and azithromycin in human embryonic stem cell-derived cardiomyocytes
por: Kim, Ye Seul, et al.
Publicado: (2020)

Correction: An integrated characterization of contractile, electrophysiological and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes
por: Wang, Ruiying, et al.
Publicado: (2023)

Characterization of the molecular mechanisms underlying azithromycin‐induced cardiotoxicity using human‐induced pluripotent stem cell‐derived cardiomyocytes
por: Wang, Xiaochen, et al.
Publicado: (2021)

Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes
por: Chaudhari, Umesh, et al.
Publicado: (2017)

Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells
por: Meng, Ya, et al.
Publicado: (2021)

Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure
por: Gherghiceanu, Mihaela, et al.
Publicado: (2011)

Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells
por: Liu, Rui, et al.
Publicado: (2020)

Cardiotoxicity and Heart Failure: Lessons from Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Anticancer Drugs
por: Sachinidis, Agapios
Publicado: (2020)

Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes
por: Grafton, Francis, et al.
Publicado: (2021)

Chronic Cardiotoxicity Assays Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs)
por: Narkar, Akshay, et al.
Publicado: (2022)

Qualitative transcriptional signatures for evaluating the maturity degree of pluripotent stem cell-derived cardiomyocytes
por: Chen, Rou, et al.
Publicado: (2019)

Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes
por: Christidi, Effimia, et al.
Publicado: (2020)

Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products
por: Simms, Liam, et al.
Publicado: (2022)

Epigenetic Regulation of Cardiomyocyte Differentiation from Embryonic and Induced Pluripotent Stem Cells
por: Kim, Yong-Jin, et al.
Publicado: (2021)

Losartan protects human stem cell-derived cardiomyocytes from angiotensin II-induced alcoholic cardiotoxicity
por: Song, Yuanxiu, et al.
Publicado: (2022)

Environmental Alterations during Embryonic Development: Studying the Impact of Stressors on Pluripotent Stem Cell-Derived Cardiomyocytes
por: Lamberto, Federica, et al.
Publicado: (2021)

Investigating and Resolving Cardiotoxicity Induced by COVID‐19 Treatments using Human Pluripotent Stem Cell‐Derived Cardiomyocytes and Engineered Heart Tissues
por: Xu, He, et al.
Publicado: (2022)

Transplantation of human induced pluripotent stem cell-derived cardiomyocytes improves myocardial function and reverses ventricular remodeling in infarcted rat hearts
por: Guan, Xumin, et al.
Publicado: (2020)

Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes
por: Lee, Hyang-Ae, et al.
Publicado: (2018)

Electrophysiological Properties of Tetraploid Cardiomyocytes Derived from Murine Pluripotent Stem Cells Generated by Fusion of Adult Somatic Cells with Embryonic Stem Cells
por: Xu, Guoxing, et al.
Publicado: (2023)

Automated Electrophysiological and Pharmacological Evaluation of Human Pluripotent Stem Cell-Derived Cardiomyocytes
por: Rajamohan, Divya, et al.
Publicado: (2016)

Correction to: Transplantation of human induced pluripotent stem cell-derived cardiomyocytes improves myocardial function and reverses ventricular remodeling in infarcted rat hearts
por: Guan, Xumin, et al.
Publicado: (2020)

Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes
por: Liu, Jianwei, et al.
Publicado: (2012)

Maturation of pluripotent stem cell derived cardiomyocytes: The new challenge
por: Aigha, Idil, et al.
Publicado: (2016)

Cardiac Regeneration with Human Pluripotent Stem Cell-Derived Cardiomyocytes
por: Park, Misun, et al.
Publicado: (2018)

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons
por: Chuang, Wenpo, et al.
Publicado: (2017)

Mitochondrial Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes
por: Dai, Dao-Fu, et al.
Publicado: (2017)

In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives
por: Kamga Kapchoup, Michelle Vanessa, et al.
Publicado: (2023)

Techniques of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell Derivation
por: Lewandowski, Jarosław, et al.
Publicado: (2016)

Ranolazine rescues the heart failure phenotype of PLN-deficient human pluripotent stem cell-derived cardiomyocytes
por: Jiang, Youxu, et al.
Publicado: (2022)

Aconitine-induced cardiac arrhythmia in human induced pluripotent stem cell-derived cardiomyocytes
por: Zhang, Feng, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_psdf77jk01pqo6t0dcudm37c0d