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CRISPR-targeted genome editing of mesenchymal stem cell-derived therapies for type 1 diabetes: a path to clinical success?

Due to their ease of isolation, differentiation capabilities, and immunomodulatory properties, the therapeutic potential of mesenchymal stem cells (MSCs) has been assessed in numerous pre-clinical and clinical settings. Currently, whole pancreas or islet transplantation is the only cure for people w...

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Detalles Bibliográficos
Autores principales: Gerace, Dario, Martiniello-Wilks, Rosetta, Nassif, Najah Therese, Lal, Sara, Steptoe, Raymond, Simpson, Ann Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345178/
https://www.ncbi.nlm.nih.gov/pubmed/28279194
http://dx.doi.org/10.1186/s13287-017-0511-8

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