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CRISPR-targeted genome editing of mesenchymal stem cell-derived therapies for type 1 diabetes: a path to clinical success?
Due to their ease of isolation, differentiation capabilities, and immunomodulatory properties, the therapeutic potential of mesenchymal stem cells (MSCs) has been assessed in numerous pre-clinical and clinical settings. Currently, whole pancreas or islet transplantation is the only cure for people w...
Autores principales: | Gerace, Dario, Martiniello-Wilks, Rosetta, Nassif, Najah Therese, Lal, Sara, Steptoe, Raymond, Simpson, Ann Margaret |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345178/ https://www.ncbi.nlm.nih.gov/pubmed/28279194 http://dx.doi.org/10.1186/s13287-017-0511-8 |
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