Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice

We previously demonstrated that transplantation of murine neural stem cells (NSCs) can improve motor and cognitive function in a transgenic model of Dementia with Lewy Bodies (DLB). These benefits occurred without changes in human α-synuclein pathology and were mediated in part by stem cell-induced...

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Detalles Bibliográficos
Autores principales: Lakatos, Anita, Goldberg, Natalie R. S., Blurton-Jones, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345195/
https://www.ncbi.nlm.nih.gov/pubmed/28283027
http://dx.doi.org/10.1186/s40478-017-0421-0

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