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Forkhead-box transcription factor 1 affects the apoptosis of natural regulatory T cells by controlling Aven expression

BACKGROUND: Regulatory T (Treg) cells play important roles in autoimmune diseases, cancer, and organ transplantation. Forkhead box protein o1 (Foxo1) and IL-7Rα(CD127) are closely related to the homeostasis of Treg cells. However, the mechanism underlying Treg proliferation and activation remains un...

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Detalles Bibliográficos
Autores principales: Cai, Zhitao, Liu, Hong, Wu, Xiongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345239/
https://www.ncbi.nlm.nih.gov/pubmed/28283017
http://dx.doi.org/10.1186/s12865-017-0198-8