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Forkhead-box transcription factor 1 affects the apoptosis of natural regulatory T cells by controlling Aven expression
BACKGROUND: Regulatory T (Treg) cells play important roles in autoimmune diseases, cancer, and organ transplantation. Forkhead box protein o1 (Foxo1) and IL-7Rα(CD127) are closely related to the homeostasis of Treg cells. However, the mechanism underlying Treg proliferation and activation remains un...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345239/ https://www.ncbi.nlm.nih.gov/pubmed/28283017 http://dx.doi.org/10.1186/s12865-017-0198-8 |