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A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy

BACKGROUND: Despite improved clinical outcomes seen following antiretroviral therapy (ART), resting CD4+ T cells continue to harbor latent human immunodeficiency virus type one (HIV-1). However, such cells are not likely the solitary viral reservoir and as such defining where and how others harbor v...

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Detalles Bibliográficos
Autores principales: Araínga, Mariluz, Edagwa, Benson, Mosley, R. Lee, Poluektova, Larisa Y., Gorantla, Santhi, Gendelman, Howard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345240/
https://www.ncbi.nlm.nih.gov/pubmed/28279181
http://dx.doi.org/10.1186/s12977-017-0344-7