Cargando…
Gain of power of the general regression model compared to Cochran-Armitage Trend tests: simulation study and application to bipolar disorder
BACKGROUND: Most genome-wide association studies assumed an additive model of inheritance which may result in significant loss of power when there is a strong departure from additivity. The General Regression Model (GRM), which allows performing an assumption-free test for association by testing for...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345257/ https://www.ncbi.nlm.nih.gov/pubmed/28283021 http://dx.doi.org/10.1186/s12863-017-0486-6 |