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Xanthine Oxidoreductase in Drug Metabolism: Beyond a Role as a Detoxifying Enzyme
The enzyme xanthine oxidoreductase (XOR) catalyzes the last two steps of purine catabolism in the highest uricotelic primates. XOR is an enzyme with dehydrogenase activity that, in mammals, may be converted into oxidase activity under a variety of pathophysiologic conditions. XOR activity is highly...
Autores principales: | Battelli, Maria Giulia, Polito, Letizia, Bortolotti, Massimo, Bolognesi, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345321/ https://www.ncbi.nlm.nih.gov/pubmed/27458036 http://dx.doi.org/10.2174/0929867323666160725091915 |
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