Cargando…

Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis

The purpose of this study was to evaluate the ability of an aperture complexity metric for volumetric‐modulated arc therapy (VMAT) plans to predict plan delivery accuracy. We developed a complexity analysis tool as a plug‐in script to Varian's Eclipse treatment planning system. This script repo...

Descripción completa

Detalles Bibliográficos
Autores principales: Younge, Kelly C., Roberts, Don, Janes, Lindsay A., Anderson, Carlos, Moran, Jean M., Matuszak, Martha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345484/
https://www.ncbi.nlm.nih.gov/pubmed/27455504
http://dx.doi.org/10.1120/jacmp.v17i4.6241
_version_ 1782513731046998016
author Younge, Kelly C.
Roberts, Don
Janes, Lindsay A.
Anderson, Carlos
Moran, Jean M.
Matuszak, Martha M.
author_facet Younge, Kelly C.
Roberts, Don
Janes, Lindsay A.
Anderson, Carlos
Moran, Jean M.
Matuszak, Martha M.
author_sort Younge, Kelly C.
collection PubMed
description The purpose of this study was to evaluate the ability of an aperture complexity metric for volumetric‐modulated arc therapy (VMAT) plans to predict plan delivery accuracy. We developed a complexity analysis tool as a plug‐in script to Varian's Eclipse treatment planning system. This script reports the modulation of plans, arcs, and individual control points for VMAT plans using a previously developed complexity metric. The calculated complexities are compared to that of 649 VMAT plans previously treated at our institution from 2013 to mid‐2015. We used the VMAT quality assurance (QA) results from the 649 treated plans, plus 62 plans that failed pretreatment QA, to validate the ability of the complexity metric to predict plan deliverability. We used a receiver operating characteristic (ROC) analysis to determine an appropriate complexity threshold value above which a plan should be considered for reoptimization before it moves further through our planning workflow. The average complexity metric for the 649 treated plans analyzed with the script was [Formula: see text] with a standard deviation of [Formula: see text]. We found that when using a threshold complexity value of [Formula: see text] , the true positive rate for correctly identifying plans that failed QA was 44%, and the false‐positive rate was 7%. Used clinically with this threshold, the script can identify overly modulated plans and thus prevent a significant portion of QA failures. Reducing VMAT plan complexity has a number of important clinical benefits, including improving plan deliverability and reducing treatment time. Use of the complexity metric during both the planning and QA processes can reduce the number of QA failures and improve the quality of VMAT plans used for treatment. PACS number(s): 87.55.de, 87.55.Qr, 87.56.jk
format Online
Article
Text
id pubmed-5345484
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-53454842017-03-10 Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis Younge, Kelly C. Roberts, Don Janes, Lindsay A. Anderson, Carlos Moran, Jean M. Matuszak, Martha M. J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to evaluate the ability of an aperture complexity metric for volumetric‐modulated arc therapy (VMAT) plans to predict plan delivery accuracy. We developed a complexity analysis tool as a plug‐in script to Varian's Eclipse treatment planning system. This script reports the modulation of plans, arcs, and individual control points for VMAT plans using a previously developed complexity metric. The calculated complexities are compared to that of 649 VMAT plans previously treated at our institution from 2013 to mid‐2015. We used the VMAT quality assurance (QA) results from the 649 treated plans, plus 62 plans that failed pretreatment QA, to validate the ability of the complexity metric to predict plan deliverability. We used a receiver operating characteristic (ROC) analysis to determine an appropriate complexity threshold value above which a plan should be considered for reoptimization before it moves further through our planning workflow. The average complexity metric for the 649 treated plans analyzed with the script was [Formula: see text] with a standard deviation of [Formula: see text]. We found that when using a threshold complexity value of [Formula: see text] , the true positive rate for correctly identifying plans that failed QA was 44%, and the false‐positive rate was 7%. Used clinically with this threshold, the script can identify overly modulated plans and thus prevent a significant portion of QA failures. Reducing VMAT plan complexity has a number of important clinical benefits, including improving plan deliverability and reducing treatment time. Use of the complexity metric during both the planning and QA processes can reduce the number of QA failures and improve the quality of VMAT plans used for treatment. PACS number(s): 87.55.de, 87.55.Qr, 87.56.jk John Wiley and Sons Inc. 2016-07-08 /pmc/articles/PMC5345484/ /pubmed/27455504 http://dx.doi.org/10.1120/jacmp.v17i4.6241 Text en © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Younge, Kelly C.
Roberts, Don
Janes, Lindsay A.
Anderson, Carlos
Moran, Jean M.
Matuszak, Martha M.
Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis
title Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis
title_full Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis
title_fullStr Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis
title_full_unstemmed Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis
title_short Predicting deliverability of volumetric‐modulated arc therapy (VMAT) plans using aperture complexity analysis
title_sort predicting deliverability of volumetric‐modulated arc therapy (vmat) plans using aperture complexity analysis
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345484/
https://www.ncbi.nlm.nih.gov/pubmed/27455504
http://dx.doi.org/10.1120/jacmp.v17i4.6241
work_keys_str_mv AT youngekellyc predictingdeliverabilityofvolumetricmodulatedarctherapyvmatplansusingaperturecomplexityanalysis
AT robertsdon predictingdeliverabilityofvolumetricmodulatedarctherapyvmatplansusingaperturecomplexityanalysis
AT janeslindsaya predictingdeliverabilityofvolumetricmodulatedarctherapyvmatplansusingaperturecomplexityanalysis
AT andersoncarlos predictingdeliverabilityofvolumetricmodulatedarctherapyvmatplansusingaperturecomplexityanalysis
AT moranjeanm predictingdeliverabilityofvolumetricmodulatedarctherapyvmatplansusingaperturecomplexityanalysis
AT matuszakmartham predictingdeliverabilityofvolumetricmodulatedarctherapyvmatplansusingaperturecomplexityanalysis