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The Potential Role of Lysosomal Sequestration in Sunitinib Resistance of Renal Cell Cancer
Renal cell carcinoma (RCC) is a highly vascularized tumor type, which is often associated with inactivated mutations in the von Hippel-Lindau gene that drives proangiogenic signaling pathways. As such, new therapies for the treatment of RCC have largely been focused on blocking angiogenesis. Sunitin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Codon Publications
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345522/ https://www.ncbi.nlm.nih.gov/pubmed/28326274 http://dx.doi.org/10.15586/jkcvhl.2015.44 |