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A novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation

p53‐Transcriptional‐regulated proteins interact with a large number of other signal transduction pathways in the cell, and a number of positive and negative autoregulatory feedback loops act upon the p53 response. P53 directly controls the POMC/α‐MSH productions induced by ultraviolet (UV) and is as...

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Detalles Bibliográficos
Autores principales:	Zhou, Ding'an, Wei, Zhiyun, Kuang, Zhongshu, Luo, Huangchao, Ma, Jiangshu, Zeng, Xing, Wang, Ke, Liu, Beizhong, Gong, Fang, Wang, Jing, Lei, Shanchuan, Wang, Dongsheng, Zeng, Jiawei, Wang, Teng, He, Yong, Yuan, Yongqiang, Dai, Hongying, He, Lin, Xing, Qinghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345616/ https://www.ncbi.nlm.nih.gov/pubmed/27885802 http://dx.doi.org/10.1111/jcmm.13022

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