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Brain‐derived neurotrophic factor attenuates doxorubicin‐induced cardiac dysfunction through activating Akt signalling in rats

The clinical application of doxorubicin (Dox) is limited by its adverse effect of cardiotoxicity. Previous studies have suggested the cardioprotective effect of brain‐derived neurotrophic factor (BDNF). We hypothesize that BDNF could protect against Dox‐induced cardiotoxicity. Sprague Dawley rats we...

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Detalles Bibliográficos
Autores principales:	Hang, Pengzhou, Zhao, Jing, Sun, Li, Li, Minghui, Han, Yu, Du, Zhimin, Li, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345637/ https://www.ncbi.nlm.nih.gov/pubmed/28098423 http://dx.doi.org/10.1111/jcmm.13012

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