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Transient CREB-mediated transcription is key in direct neuronal reprogramming

Combinations of neuronal determinants and/or small-molecules such as Forskolin (Fk) can be used to convert different cell types into neurons. As Fk is known to activate cAMP-dependent pathways including CREB-activity, we aimed here to determine the role of CREB in reprogramming – including its tempo...

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Detalles Bibliográficos
Autores principales: Gascón, Sergio, Ortega, Felipe, Götz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345748/
https://www.ncbi.nlm.nih.gov/pubmed/28321434
http://dx.doi.org/10.1080/23262133.2017.1285383

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