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Transient CREB-mediated transcription is key in direct neuronal reprogramming
Combinations of neuronal determinants and/or small-molecules such as Forskolin (Fk) can be used to convert different cell types into neurons. As Fk is known to activate cAMP-dependent pathways including CREB-activity, we aimed here to determine the role of CREB in reprogramming – including its tempo...
Autores principales: | Gascón, Sergio, Ortega, Felipe, Götz, Magdalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345748/ https://www.ncbi.nlm.nih.gov/pubmed/28321434 http://dx.doi.org/10.1080/23262133.2017.1285383 |
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