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Amyloid Precursor Protein family as unconventional Go-coupled receptors and the control of neuronal motility
Cleavage of the Amyloid Precursor Protein (APP) generates amyloid peptides that accumulate in Alzheimer Disease (AD), but APP is also upregulated by developing and injured neurons, suggesting that it regulates neuronal motility. APP can also function as a G protein-coupled receptor that signals via...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345750/ https://www.ncbi.nlm.nih.gov/pubmed/28321435 http://dx.doi.org/10.1080/23262133.2017.1288510 |