Increasing efficiency of preclinical research by group sequential designs

Despite the potential benefits of sequential designs, studies evaluating treatments or experimental manipulations in preclinical experimental biomedicine almost exclusively use classical block designs. Our aim with this article is to bring the existing methodology of group sequential designs to the...

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Detalles Bibliográficos
Autores principales: Neumann, Konrad, Grittner, Ulrike, Piper, Sophie K., Rex, Andre, Florez-Vargas, Oscar, Karystianis, George, Schneider, Alice, Wellwood, Ian, Siegerink, Bob, Ioannidis, John P. A., Kimmelman, Jonathan, Dirnagl, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345756/
https://www.ncbi.nlm.nih.gov/pubmed/28282371
http://dx.doi.org/10.1371/journal.pbio.2001307

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