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The renal phenotype of allopurinol-treated HPRT-deficient mouse

Excess of uric acid is mainly treated with xanthine oxidase (XO) inhibitors, also called uricostatics because they block the conversion of hypoxanthine and xanthine into urate. Normally, accumulation of upstream metabolites is prevented by the hypoxanthine-guanine phosphoribosyltransferase (HPRT) en...

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Detalles Bibliográficos
Autores principales:	Zennaro, Cristina, Tonon, Federica, Zarattini, Paola, Clai, Milan, Corbelli, Alessandro, Carraro, Michele, Marchetti, Marialaura, Ronda, Luca, Paredi, Gianluca, Rastaldi, Maria Pia, Percudani, Riccardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345830/ https://www.ncbi.nlm.nih.gov/pubmed/28282408 http://dx.doi.org/10.1371/journal.pone.0173512

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