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Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma

OBJECTIVE: The aim of the present study was to determine whether a combination of anti-HIV drugs – tenofovir (TFV), lopinavir (LPV) and ritonavir (RTV) – in a lipid-stabilized nanosuspension (called TLC-ART101) could enhance and sustain intracellular drug levels and exposures in lymph node and blood...

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Detalles Bibliográficos
Autores principales:	Kraft, John C., McConnachie, Lisa A., Koehn, Josefin, Kinman, Loren, Collins, Carol, Shen, Danny D., Collier, Ann C., Ho, Rodney J.Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Basic Science: Concise Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345888/ https://www.ncbi.nlm.nih.gov/pubmed/28099191 http://dx.doi.org/10.1097/QAD.0000000000001405

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