Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin

Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU) and oxaliplatin. The two anticancer drugs mediate their the...

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Detalles Bibliográficos
Autores principales: Wiegering, Armin, Matthes, Niels, Mühling, Bettina, Koospal, Monika, Quenzer, Anne, Peter, Stephanie, Germer, Christoph-Thomas, Linnebacher, Michael, Otto, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345961/
https://www.ncbi.nlm.nih.gov/pubmed/28284059
http://dx.doi.org/10.1016/j.neo.2017.01.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345961/
https://www.ncbi.nlm.nih.gov/pubmed/28284059
http://dx.doi.org/10.1016/j.neo.2017.01.007

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