Polychlorinated biphenyls-153 induces metabolic dysfunction through activation of ROS/NF-κB signaling via downregulation of HNF1b

Polychlorinated biphenyls (PCB) is a major type of persistent organic pollutants (POPs) that act as endocrine-disrupting chemicals. In the current study, we examined the mechanism underlying the effect of PCB-153 on glucose and lipid metabolism in vivo and in vitro. We found that PCB-153 induced per...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Yu, Weihua, Meng, Fansen, Mi, Jie, Peng, Jie, Liu, Jiangzheng, Zhang, Xiaodi, Hai, Chunxu, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345977/
https://www.ncbi.nlm.nih.gov/pubmed/28285191
http://dx.doi.org/10.1016/j.redox.2017.02.026

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