Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device

Atrial fibrillation (AF) remains an important clinical problem with severe complications such as stroke, which especially harms those with risk factors as calculated by the CHADS(2) or CHA(2)DS(2)-VASc. Until now, no therapy has proven 100% effective against AF. Since the left atrial appendage (LAA)...

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Autores principales: Alipour, Arash, Wintgens, Lisette I S, Swaans, Martin J, Balt, Jippe C, Rensing, Benno J W M, Boersma, Lucas V A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345987/
https://www.ncbi.nlm.nih.gov/pubmed/28293114
http://dx.doi.org/10.2147/VHRM.S89213
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author Alipour, Arash
Wintgens, Lisette I S
Swaans, Martin J
Balt, Jippe C
Rensing, Benno J W M
Boersma, Lucas V A
author_facet Alipour, Arash
Wintgens, Lisette I S
Swaans, Martin J
Balt, Jippe C
Rensing, Benno J W M
Boersma, Lucas V A
author_sort Alipour, Arash
collection PubMed
description Atrial fibrillation (AF) remains an important clinical problem with severe complications such as stroke, which especially harms those with risk factors as calculated by the CHADS(2) or CHA(2)DS(2)-VASc. Until now, no therapy has proven 100% effective against AF. Since the left atrial appendage (LAA) is the most prominent nonvalvular AF-related thromboembolic source and (novel) oral anticoagulant [(N)OAC] carries the hazard of bleeding, LAA occlusion may be an alternative, especially in patients who are ineligible for (N)OAC therapy. In this review, we discuss several LAA occlusion techniques with a focus on the Watchman device since this device is the most thoroughly studied device of all.
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spelling pubmed-53459872017-03-14 Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device Alipour, Arash Wintgens, Lisette I S Swaans, Martin J Balt, Jippe C Rensing, Benno J W M Boersma, Lucas V A Vasc Health Risk Manag Review Atrial fibrillation (AF) remains an important clinical problem with severe complications such as stroke, which especially harms those with risk factors as calculated by the CHADS(2) or CHA(2)DS(2)-VASc. Until now, no therapy has proven 100% effective against AF. Since the left atrial appendage (LAA) is the most prominent nonvalvular AF-related thromboembolic source and (novel) oral anticoagulant [(N)OAC] carries the hazard of bleeding, LAA occlusion may be an alternative, especially in patients who are ineligible for (N)OAC therapy. In this review, we discuss several LAA occlusion techniques with a focus on the Watchman device since this device is the most thoroughly studied device of all. Dove Medical Press 2017-03-06 /pmc/articles/PMC5345987/ /pubmed/28293114 http://dx.doi.org/10.2147/VHRM.S89213 Text en © 2017 Alipour et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Alipour, Arash
Wintgens, Lisette I S
Swaans, Martin J
Balt, Jippe C
Rensing, Benno J W M
Boersma, Lucas V A
Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device
title Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device
title_full Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device
title_fullStr Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device
title_full_unstemmed Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device
title_short Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device
title_sort novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the watchman closure device
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345987/
https://www.ncbi.nlm.nih.gov/pubmed/28293114
http://dx.doi.org/10.2147/VHRM.S89213
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