Cargando…
Glucocorticoid receptor expression in 20 solid tumor types using immunohistochemistry assay
BACKGROUND: Glucocorticoid receptor (GR) activity plays a role in many aspects of human physiology and may play a crucial role in chemotherapy resistance in a wide variety of solid tumors. A novel immunohistochemistry (IHC) based assay has been previously developed and validated in order to assess G...
Autores principales: | Block, Thaddeus S, Murphy, Tiffany I, Munster, Pamela N, Nguyen, Dat P, Lynch, Frank J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345989/ https://www.ncbi.nlm.nih.gov/pubmed/28293120 http://dx.doi.org/10.2147/CMAR.S124475 |
Ejemplares similares
-
Development and validation of an immunohistochemistry assay to assess glucocorticoid receptor expression for clinical trials of mifepristone in breast cancer
por: Baker, Gabrielle M, et al.
Publicado: (2015) -
Glucocorticoid Receptor Antagonism Upregulates Somatostatin Receptor Subtype 2 Expression in ACTH-Producing Neuroendocrine Tumors: New Insight Based on the Selective Glucocorticoid Receptor Modulator Relacorilant
por: Pivonello, Rosario, et al.
Publicado: (2022) -
Mifepristone Plasma Level and Glucocorticoid Receptor Antagonism Associated With Response in Patients With Psychotic Depression
por: Block, Thaddeus, et al.
Publicado: (2017) -
Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells
por: Greenstein, Andrew E., et al.
Publicado: (2021) -
Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors
por: Munster, Pamela N., et al.
Publicado: (2022)