Cargando…
Biochemistry in Endeavor Adventure Racers Study (BEARS)
Background: Adventure sports events consist of a combination of two or more endurance disciplines, such as orienteering, running, and rock climbing, that range from a day’s to a week’s duration. No studies have examined acute kidney injury (AKI) in adventure sports athletes. Objectives: To describe...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346018/ https://www.ncbi.nlm.nih.gov/pubmed/28348942 http://dx.doi.org/10.7759/cureus.1024 |
_version_ | 1782513819683127296 |
---|---|
author | Wetschler, Matthew Radler, David Christensen, Mark Lipman, Grant |
author_facet | Wetschler, Matthew Radler, David Christensen, Mark Lipman, Grant |
author_sort | Wetschler, Matthew |
collection | PubMed |
description | Background: Adventure sports events consist of a combination of two or more endurance disciplines, such as orienteering, running, and rock climbing, that range from a day’s to a week’s duration. No studies have examined acute kidney injury (AKI) in adventure sports athletes. Objectives: To describe the prevalence of AKI in participants in the Endeavor Team Challenge, a 30-hour, 40-mile adventure race. Methods: In this prospective observational study, body weights were recorded at race registration. At the finish line, blood sample results by point-of-care testing and weights were recorded. Changes in serum creatinine (Cr) from an estimated baseline value and severity of AKI were calculated, with “risk of injury” defined as 1.5 x baseline Cr, and “injury” defined as 2 x baseline Cr. These two categories of AKI were combined to calculate the total prevalence. Results: There were 88 enrolled study participants with complete data available on 46 (52%). The mean age of those enrolled in the study was 36.8 years (+/- 7.7), 90% were males, and body mass index (BMI) was 25.7 kg/m(2) (+/- 2.4). Of the competitors who completed the study, 34 (73%) had some degree of AKI, with 27 (58%) found to be at "risk" and seven (15%) with "injury". There was a significant correlation between weight loss and elevated Cr (r = -0.29, p = 0.047), with a trend towards nonsteroidal anti-inflammatory drug (NSAID) use being correlated with AKI (p = 0.058). Conclusion: Acute kidney injury was observed in the majority of the Endeavor Team Challenge adventure racers, similar to what has been observed in multistage ultramarathons, and greater than after standard marathons and single-stage ultramarathons. |
format | Online Article Text |
id | pubmed-5346018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-53460182017-03-27 Biochemistry in Endeavor Adventure Racers Study (BEARS) Wetschler, Matthew Radler, David Christensen, Mark Lipman, Grant Cureus Emergency Medicine Background: Adventure sports events consist of a combination of two or more endurance disciplines, such as orienteering, running, and rock climbing, that range from a day’s to a week’s duration. No studies have examined acute kidney injury (AKI) in adventure sports athletes. Objectives: To describe the prevalence of AKI in participants in the Endeavor Team Challenge, a 30-hour, 40-mile adventure race. Methods: In this prospective observational study, body weights were recorded at race registration. At the finish line, blood sample results by point-of-care testing and weights were recorded. Changes in serum creatinine (Cr) from an estimated baseline value and severity of AKI were calculated, with “risk of injury” defined as 1.5 x baseline Cr, and “injury” defined as 2 x baseline Cr. These two categories of AKI were combined to calculate the total prevalence. Results: There were 88 enrolled study participants with complete data available on 46 (52%). The mean age of those enrolled in the study was 36.8 years (+/- 7.7), 90% were males, and body mass index (BMI) was 25.7 kg/m(2) (+/- 2.4). Of the competitors who completed the study, 34 (73%) had some degree of AKI, with 27 (58%) found to be at "risk" and seven (15%) with "injury". There was a significant correlation between weight loss and elevated Cr (r = -0.29, p = 0.047), with a trend towards nonsteroidal anti-inflammatory drug (NSAID) use being correlated with AKI (p = 0.058). Conclusion: Acute kidney injury was observed in the majority of the Endeavor Team Challenge adventure racers, similar to what has been observed in multistage ultramarathons, and greater than after standard marathons and single-stage ultramarathons. Cureus 2017-02-11 /pmc/articles/PMC5346018/ /pubmed/28348942 http://dx.doi.org/10.7759/cureus.1024 Text en Copyright © 2017, Wetschler et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Emergency Medicine Wetschler, Matthew Radler, David Christensen, Mark Lipman, Grant Biochemistry in Endeavor Adventure Racers Study (BEARS) |
title | Biochemistry in Endeavor Adventure Racers Study (BEARS) |
title_full | Biochemistry in Endeavor Adventure Racers Study (BEARS) |
title_fullStr | Biochemistry in Endeavor Adventure Racers Study (BEARS) |
title_full_unstemmed | Biochemistry in Endeavor Adventure Racers Study (BEARS) |
title_short | Biochemistry in Endeavor Adventure Racers Study (BEARS) |
title_sort | biochemistry in endeavor adventure racers study (bears) |
topic | Emergency Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346018/ https://www.ncbi.nlm.nih.gov/pubmed/28348942 http://dx.doi.org/10.7759/cureus.1024 |
work_keys_str_mv | AT wetschlermatthew biochemistryinendeavoradventureracersstudybears AT radlerdavid biochemistryinendeavoradventureracersstudybears AT christensenmark biochemistryinendeavoradventureracersstudybears AT lipmangrant biochemistryinendeavoradventureracersstudybears |