Cargando…

Biochemistry in Endeavor Adventure Racers Study (BEARS)

Background: Adventure sports events consist of a combination of two or more endurance disciplines, such as orienteering, running, and rock climbing, that range from a day’s to a week’s duration. No studies have examined acute kidney injury (AKI) in adventure sports athletes. Objectives: To describe...

Descripción completa

Detalles Bibliográficos
Autores principales: Wetschler, Matthew, Radler, David, Christensen, Mark, Lipman, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346018/
https://www.ncbi.nlm.nih.gov/pubmed/28348942
http://dx.doi.org/10.7759/cureus.1024
_version_ 1782513819683127296
author Wetschler, Matthew
Radler, David
Christensen, Mark
Lipman, Grant
author_facet Wetschler, Matthew
Radler, David
Christensen, Mark
Lipman, Grant
author_sort Wetschler, Matthew
collection PubMed
description Background: Adventure sports events consist of a combination of two or more endurance disciplines, such as orienteering, running, and rock climbing, that range from a day’s to a week’s duration. No studies have examined acute kidney injury (AKI) in adventure sports athletes. Objectives: To describe the prevalence of AKI in participants in the Endeavor Team Challenge, a 30-hour, 40-mile adventure race. Methods: In this prospective observational study, body weights were recorded at race registration. At the finish line, blood sample results by point-of-care testing and weights were recorded. Changes in serum creatinine (Cr) from an estimated baseline value and severity of AKI were calculated, with “risk of injury” defined as 1.5 x baseline Cr, and “injury” defined as 2 x baseline Cr. These two categories of AKI were combined to calculate the total prevalence.  Results: There were 88 enrolled study participants with complete data available on 46 (52%). The mean age of those enrolled in the study was 36.8 years (+/- 7.7), 90% were males, and body mass index (BMI) was 25.7 kg/m(2) (+/- 2.4). Of the competitors who completed the study, 34 (73%) had some degree of AKI, with 27 (58%) found to be at "risk" and seven (15%) with "injury". There was a significant correlation between weight loss and elevated Cr (r = -0.29, p = 0.047), with a trend towards nonsteroidal anti-inflammatory drug (NSAID) use being correlated with AKI (p = 0.058). Conclusion: Acute kidney injury was observed in the majority of the Endeavor Team Challenge adventure racers, similar to what has been observed in multistage ultramarathons, and greater than after standard marathons and single-stage ultramarathons.
format Online
Article
Text
id pubmed-5346018
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-53460182017-03-27 Biochemistry in Endeavor Adventure Racers Study (BEARS) Wetschler, Matthew Radler, David Christensen, Mark Lipman, Grant Cureus Emergency Medicine Background: Adventure sports events consist of a combination of two or more endurance disciplines, such as orienteering, running, and rock climbing, that range from a day’s to a week’s duration. No studies have examined acute kidney injury (AKI) in adventure sports athletes. Objectives: To describe the prevalence of AKI in participants in the Endeavor Team Challenge, a 30-hour, 40-mile adventure race. Methods: In this prospective observational study, body weights were recorded at race registration. At the finish line, blood sample results by point-of-care testing and weights were recorded. Changes in serum creatinine (Cr) from an estimated baseline value and severity of AKI were calculated, with “risk of injury” defined as 1.5 x baseline Cr, and “injury” defined as 2 x baseline Cr. These two categories of AKI were combined to calculate the total prevalence.  Results: There were 88 enrolled study participants with complete data available on 46 (52%). The mean age of those enrolled in the study was 36.8 years (+/- 7.7), 90% were males, and body mass index (BMI) was 25.7 kg/m(2) (+/- 2.4). Of the competitors who completed the study, 34 (73%) had some degree of AKI, with 27 (58%) found to be at "risk" and seven (15%) with "injury". There was a significant correlation between weight loss and elevated Cr (r = -0.29, p = 0.047), with a trend towards nonsteroidal anti-inflammatory drug (NSAID) use being correlated with AKI (p = 0.058). Conclusion: Acute kidney injury was observed in the majority of the Endeavor Team Challenge adventure racers, similar to what has been observed in multistage ultramarathons, and greater than after standard marathons and single-stage ultramarathons. Cureus 2017-02-11 /pmc/articles/PMC5346018/ /pubmed/28348942 http://dx.doi.org/10.7759/cureus.1024 Text en Copyright © 2017, Wetschler et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Wetschler, Matthew
Radler, David
Christensen, Mark
Lipman, Grant
Biochemistry in Endeavor Adventure Racers Study (BEARS)
title Biochemistry in Endeavor Adventure Racers Study (BEARS)
title_full Biochemistry in Endeavor Adventure Racers Study (BEARS)
title_fullStr Biochemistry in Endeavor Adventure Racers Study (BEARS)
title_full_unstemmed Biochemistry in Endeavor Adventure Racers Study (BEARS)
title_short Biochemistry in Endeavor Adventure Racers Study (BEARS)
title_sort biochemistry in endeavor adventure racers study (bears)
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346018/
https://www.ncbi.nlm.nih.gov/pubmed/28348942
http://dx.doi.org/10.7759/cureus.1024
work_keys_str_mv AT wetschlermatthew biochemistryinendeavoradventureracersstudybears
AT radlerdavid biochemistryinendeavoradventureracersstudybears
AT christensenmark biochemistryinendeavoradventureracersstudybears
AT lipmangrant biochemistryinendeavoradventureracersstudybears