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Cohesin biology meets the loop extrusion model

Extensive research has revealed that cohesin acts as a topological device, trapping chromosomal DNA within a large tripartite ring. In so doing, cohesin contributes to the formation of compact and organized genomes. How exactly the cohesin subunits interact, how it opens, closes, and translocates on...

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Detalles Bibliográficos
Autores principales:	Barrington, Christopher, Finn, Ronald, Hadjur, Suzana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346154/ https://www.ncbi.nlm.nih.gov/pubmed/28210885 http://dx.doi.org/10.1007/s10577-017-9550-3

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