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Silencing markers are retained on pericentric heterochromatin during murine primordial germ cell development

BACKGROUND: In the nuclei of most mammalian cells, pericentric heterochromatin is characterized by DNA methylation, histone modifications such as H3K9me3 and H4K20me3, and specific binding proteins like heterochromatin-binding protein 1 isoforms (HP1 isoforms). Maintenance of this specialized chroma...

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Detalles Bibliográficos
Autores principales:	Magaraki, Aristea, van der Heijden, Godfried, Sleddens-Linkels, Esther, Magarakis, Leonidas, van Cappellen, Wiggert A., Peters, Antoine H. F. M., Gribnau, Joost, Baarends, Willy M., Eijpe, Maureen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346203/ https://www.ncbi.nlm.nih.gov/pubmed/28293300 http://dx.doi.org/10.1186/s13072-017-0119-3

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