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Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes

BACKGROUND: Airway fibrosis is one of the pathological features of chronic obstructive pulmonary disease (COPD), and recent studies revealed that acetylcholine plays an important role in the development of airway remodeling by stimulating proliferation and collagen synthesis of lung fibroblasts. Thi...

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Detalles Bibliográficos
Autores principales:	Namba, Yukiko, Togo, Shinsaku, Tulafu, Miniwan, Kadoya, Kotaro, Nagahama, Kumi Yoneda, Taka, Hikari, Kaga, Naoko, Orimo, Akira, Liu, Xiangde, Takahashi, Kazuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346259/ https://www.ncbi.nlm.nih.gov/pubmed/28284212 http://dx.doi.org/10.1186/s12931-017-0529-6

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