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Defective Anks1a disrupts the export of receptor tyrosine kinases from the endoplasmic reticulum
EphA2 has been implicated in amplifying ErbB2 tumorigenic signaling. One protein that interacts with EphA2 is the Anks1a PTB adaptor. However, the precise role of Anks1a in EphA2-mediated tumorigenesis is unclear. We demonstrated that Anks1a localizes to the ER upon phosphorylation and that the Anky...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Society for Biochemistry and Molecular Biology
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346308/ https://www.ncbi.nlm.nih.gov/pubmed/27802842 http://dx.doi.org/10.5483/BMBRep.2016.49.12.186 |