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HBK-14 and HBK-15 with antidepressant-like and/or memory-enhancing properties increase serotonin levels in the hippocampus after chronic treatment in mice

5-HT(1A) and 5-HT(7) receptor ligands might have antidepressant-like properties and improve cognitive function. We previously reported significant antidepressant- and anxiolytic-like effects of two dual 5-HT(1A) and 5-HT(7) receptor antagonists in various behavioral tests in rodents. As a continuati...

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Detalles Bibliográficos
Autores principales: Pytka, Karolina, Gawlik, Katarzyna, Pawlica-Gosiewska, Dorota, Witalis, Jadwiga, Waszkielewicz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346433/
https://www.ncbi.nlm.nih.gov/pubmed/27888375
http://dx.doi.org/10.1007/s11011-016-9932-9

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