A functional signal profiling test for identifying a subset of HER2-negative breast cancers with abnormally amplified HER2 signaling activity

The results of clinical trials evaluating the efficacy of HER2 inhibitors in patients with breast cancer indicate that the correlation between HER2 receptor levels and patient outcomes is as low as 50%. The relatively weak correlation between HER2 status and response to HER2-targeting drugs suggests...

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Detalles Bibliográficos
Autores principales: Huang, Yao, Burns, David J, Rich, Benjamin E, MacNeil, Ian A, Dandapat, Abhijit, Soltani, Sajjad M., Myhre, Samantha, Sullivan, Brian F, Furcht, Leo T, Lange, Carol A, Hurvitz, Sara A, Laing, Lance G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346661/
https://www.ncbi.nlm.nih.gov/pubmed/27713176
http://dx.doi.org/10.18632/oncotarget.12480

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