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In Vivo magnetic resonance imaging of xenografted tumors using FTH1 reporter gene expression controlled by a tet-on switch

As a promising magnetic resonance imaging (MRI) reporter, ferritin has been used to track cells in vivo; however, its continuous overexpression can be cytotoxic, which restricts its application. In this study, we aimed to develop a switch to turn this genetic reporter “on” or “off” while monitoring...

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Detalles Bibliográficos
Autores principales: He, Xiaoya, Cai, Jinhua, Li, Hao, Liu, Bo, Qin, Yong, Zhong, Yi, Wang, Longlun, Liao, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346662/
https://www.ncbi.nlm.nih.gov/pubmed/27732930
http://dx.doi.org/10.18632/oncotarget.12519