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Metformin treatment reduces temozolomide resistance of glioblastoma cells

It has been reported that metformin acts synergistically with temozolomide (TMZ) to inhibit proliferation of glioma cells including glioblastoma multiforme (GBM). However, the molecular mechanism underlying how metformin exerts its anti-cancer effects remains elusive. We used a combined experimental...

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Detalles Bibliográficos
Autores principales:	Yang, Seung Ho, Li, Shenglan, Lu, Guangrong, Xue, Haipeng, Kim, Dong H., Zhu, Jay-Jiguang, Liu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346677/ https://www.ncbi.nlm.nih.gov/pubmed/27791206 http://dx.doi.org/10.18632/oncotarget.12859

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