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Delivery of a peptide-drug conjugate targeting the blood brain barrier improved the efficacy of paclitaxel against glioma

The challenge of effectively delivering therapeutic agents to the brain has created an entire field of active research devoted to overcoming the blood brain barrier (BBB) and efficiently delivering drugs to the brain. Angiopep-2 can trigger transcytosis and traverse the BBB by recognizing low-densit...

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Detalles Bibliográficos
Autores principales: Li, Ying, Zheng, Xuemin, Gong, Min, Zhang, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346723/
https://www.ncbi.nlm.nih.gov/pubmed/27765902
http://dx.doi.org/10.18632/oncotarget.12708

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