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Deubiquitinase USP9X deubiquitinates β-catenin and promotes high grade glioma cell growth
β-catenin is a crucial signal transduction molecule in the Wnt/β-catenin signal pathway, and increased β-catenin expression has consistently been found in high grade gliomas. However, the mechanisms responsible for β-catenin overexpression have remained elusive. Here we show that the deubiquitinase...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346732/ https://www.ncbi.nlm.nih.gov/pubmed/27783990 http://dx.doi.org/10.18632/oncotarget.12819 |