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Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes

Anaplastic large cell lymphomas (ALCL) represent a peripheral T-cell lymphoma subgroup, stratified based on the presence or absence of anaplastic lymphoma kinase (ALK) chimeras. Although ALK-positive ALCLs have a more favorable outcome than ALK-negative ALCL, refractory and/or relapsed forms are com...

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Detalles Bibliográficos
Autores principales:	Boi, Michela, Todaro, Maria, Vurchio, Valentina, Yang, Shao Ning, Moon, John, Kwee, Ivo, Rinaldi, Andrea, Pan, Heng, Crescenzo, Ramona, Cheng, Mangeng, Cerchietti, Leandro, Elemento, Olivier, Riveiro, Maria E., Cvitkovic, Esteban, Bertoni, Francesco, Inghirami, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346742/ https://www.ncbi.nlm.nih.gov/pubmed/27793034 http://dx.doi.org/10.18632/oncotarget.12876

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